AUTORI: Janšáková, K., Belica, I., Rajčániová, E., Rajčáni, J., Kyselicová, K., Celušáková, H., Laznibatová, J. and Ostatníková, D. ABSTRACT: The effect of chronic stress on oxidative stress (OS) is commonly discussed while the effect of acute stress situation is not fully examined yet. The present study was aimed to analyse whether acute psychosocial strain causes
AUTORI: Reichová, A., Bačová, Z., Bukatová, S., Kokavcová, M., Melišková, V., Frimmel, K., Ostatníková, D. and Bakoš, J. ABSTRACT: Oxytocin has been suggested as a potential therapeutic agent in autism and other neuropsychiatric conditions. Although, the link between the deficit in “SH3 domain and ankyrin repeat containing protein 3” (SHANK3) and autism spectrum disorders is
AUTORI: Olešová, D., Galba, J., Piešťanský, J., Celušáková, H., Repiská, G., Babinská, K., Ostatníková, D., Katina, S. and Kováč, A. ABSTRAKT: Autism spectrum disorder is a heterogeneous neurodevelopmental disease. Currently, no biomarker of this disease is known. Diagnosis is performed through observation, standardized behavioral scales, and interviews with parents. In practice, diagnosis is often delayed
AUTORI: Konečná, B., Radošinská, J., Keményová, P. and Repiská, G. ABSTRACT: Autism spectrum disorders (ASD) diagnostic procedure still lacks a uniform biological marker. This review gathers the information on microRNAs (miRNAs) specifically as a possible source of biomarkers of ASD. Extracellular vesicles, and their subset of exosomes, are believed to be a tool of cell-to-cell
AUTORI: Ostatníková, D., Lakatošová, S., Babková, J., Hodosy, J. and Celec, P. ABSTRACT: Sex and gender matter in all aspects of life. Humans exhibit sexual dimorphism in anatomy, physiology, but also pathology. Many of the differences are due to sex chromosomes and, thus, genetics, other due to endocrine factors such as sex hormones, some are
AUTORI: Čelárová, D., Celušáková, H., Szapuová, Ž. and Ostatníková, D. ABSTRACT: Autism spectrum disorders are more common in males than females. Cause of this ratio is unknown and has been ascribed to hormonal (extreme male brain theory) or genetic (female protective model) etiology. One of the plausible explanations is the ability of girls to better
