Publications – Page 2 – Akademické centrum výskumu autizmu

- 30. DECEMBER 2021
The role of selected postsynaptic scaffolding proteins at glutamatergic synapses in autism-related animal models
AUTHORS: Melišková, V., Havránek, T., Bačová, Z. and Bakoš, J. ABSTRACT: Pathological changes in synapse formation, plasticity and development are caused by altered trafficking and assembly of postsynaptic scaffolding proteins at sites of glutamatergic and gamma-aminobutyric acid synapses, suggesting their involvement in the etiology of neurodevelopmental disorders, including autism. Several autism-related mouse models have been
- Barbara Rašková
- 2021,
- Publications
- 8. OCTOBER 2021
Potential of Salivary Biomarkers in Autism Research: A Systematic Review
AUTHORS: Janšáková, K., Kyselicová, K., Ostatníková, D. and Repiská, G. ABSTRACT: The diagnostic process for autism spectrum disorders (ASD) is based on a behavioral analysis of the suspected individual. Despite intensive research, no specific and valid biomarker has been identified for ASD, but saliva, with its advantages such as non-invasive collection, could serve as a
- Barbara Rašková
- 2021,
- Publications
- 4. MAY 2021
Autism spectrum disorder and new perspectives on the reliability of second to fourth digit ratio
AUTHORS: Kyselicová, K., Belica, I., Vidošovičová, M., Janšáková, K., Neščáková, E., Špajdel, M., Navarová, S. and Ostatníková, D. ABSTRACT: The second to fourth digit ratio (2D:4D) is according to previous studies a likely biomarker for prenatal testosterone exposure and its effect on the human brain. It was found to be linked to autism spectrum disorders
- Barbara Rašková
- 2021,
- Publications
- 24. MARCH 2021
Evaluation of 16S rRNA primer sets for characterisation of microbiota in paediatric patients with autism spectrum disorder
AUTHORS: Palkova, L. , Tomova, A., Repiska, G., Babinska, K., Bokor, B., Mikula, I.,Minarik, G., Ostatnikova, D. and Soltys. K. ABSTRACT: Intestinal microbiota is becoming a significant marker that reflects differences between health and disease status also in terms of gut-brain axis communication. Studies show that children with autism spectrum disorder (ASD) often have a mix
- Barbara Rašková
- 2021,
- Publications

- 14. JANUARY 2021
The acute effect of psychosocial stress on the level of oxidative stress in children
AUTHORS: Janšáková, K., Belica, I., Rajčániová, E., Rajčáni, J., Kyselicová, K., Celušáková, H., Laznibatová, J. and Ostatníková, D. ABSTRACT: The effect of chronic stress on oxidative stress (OS) is commonly discussed while the effect of acute stress situation is not fully examined yet. The present study was aimed to analyse whether acute psychosocial strain causes
- Barbara Rašková
- 2021,
- Publications
- 1. DECEMBER 2020
Abnormal neuronal morphology and altered synaptic proteins are restored by oxytocin in autism-related SHANK3 deficient model
AUTHORS: Reichová, A., Bačová, Z., Bukatová, S., Kokavcová, M., Melišková, V., Frimmel, K., Ostatníková, D. and Bakoš, J. ABSTRACT: Oxytocin has been suggested as a potential therapeutic agent in autism and other neuropsychiatric conditions. Although, the link between the deficit in “SH3 domain and ankyrin repeat containing protein 3” (SHANK3) and autism spectrum disorders is
- Barbara Rašková
- 2020,
- Publications
- 2. NOVEMBER 2020
A novel UHPLC-MS method targeting urinary metabolomic markers for autism spectrum disorder
AUTHORS: Olešová, D., Galba, J., Piešťanský, J., Celušáková, H., Repiská, G., Babinská, K., Ostatníková, D., Katina, S. and Kováč, A. ABSTRACT: Autism spectrum disorder is a heterogeneous neurodevelopmental disease. Currently, no biomarker of this disease is known. Diagnosis is performed through observation, standardized behavioral scales, and interviews with parents. In practice, diagnosis is often delayed
- Barbara Rašková
- 2020,
- Publications
- 25. OCTOBER 2020
Detection of disease-associated microRNAs – application for autism spectrum disorders
AUTHORS: Konečná, B., Radošinská, J., Keményová, P. and Repiská, G. ABSTRACT: Autism spectrum disorders (ASD) diagnostic procedure still lacks a uniform biological marker. This review gathers the information on microRNAs (miRNAs) specifically as a possible source of biomarkers of ASD. Extracellular vesicles, and their subset of exosomes, are believed to be a tool of cell-to-cell
- Barbara Rašková
- 2020,
- Publications