• 28. MARCH 2021
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    Sleep

    Sleep

    Children with ASD often have trouble sleeping. Their causes can be different, one of the theories assumes disruption of circadian rhythms (so-called internal biological clocks). This theory is evidenced by the differences in the levels of melatonin – a hormone that is involved in the regulation of biorhythms depending on changes in light intensity during

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    • 2. NOVEMBER 2021
    • 0
    Sex-specific microbiome and gene interactions in the pathogenesis of behavioral and gastrointestinal symptoms in the animal model of autism spectrum disorder

    Sex-specific microbiome and gene interactions in the pathogenesis of behavioral and gastrointestinal symptoms in the animal model of autism spectrum disorder

    Sex-specific microbiome and gene interactions in the pathogenesis of behavioral and gastrointestinal symptoms in the animal model of autism spectrum disorder (APVV-20-0114) Principal investigator: Doc. MUDr. Aleksandra Tomova, PhD. Annotation Autism spectrum disorder (ASD) is a complex of neurodevelopmental conditions with increasing incidence. Genetic background of ASD explains

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    • 1. JUNE 2017
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    Sex-dependent effects of letrozole on anxiety in middle-aged rats

    Sex-dependent effects of letrozole on anxiety in middle-aged rats

    AUTHORS: Borbelyova, V., E. Renczes Domonkos, M. Csongova, M. Kacmarova, D. Ostatnikova, P. Celec, and J. Hodosy ABSTRACT: Aromatase catalyzes the conversion of testosterone to estradiol and is involved in the physiological effects of sex hormones on brain function. Animal experiments have shown that the aromatase inhibitor, letrozole, can induce anxiety in young ovariectomized femalesRead more
    • 1. NOVEMBER 2021
    • 0
    Sex specific genetic-endocrine insights into autism spectrum disorder

    Sex specific genetic-endocrine insights into autism spectrum disorder

    Sex specific genetic-endocrine insights into autism spectrum disorder   the beginning of the project: 01.07.2021the end of the project: 31.12.2024   Annotation Autism spectrum disorders (ASD) are lifelong neurodevelopmental disorders characterized by social and communication deficits, as well as stereotypical and limited behavioral patterns.

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