Publications – Page 6 – Akademické centrum výskumu autizmu

- 1. MAY 2018
Adulthood with autism spectrum disorder: difficulties and challenges (Život s poruchou autistického spektra v dospelosti: problémy a výzvy)
AUTHORS: Szapuová, Ž., Belica, I., Keményová, P., Celušáková, H., Čelárová, D., Ostatníková, D. ABSTRACT: Autism Spectrum Disorder (ASD) is a life-long neurodevelopmental disorder that has a serious impact on various aspects of an individual‘s life. Deficits in social communication skills, that are characteristic for this disorder, have significant impacts on adaptability defined as fulfilling activities
- 1. APRIL 2018
Projection length stimulated by oxytocin is modulated by the inhibition of calcium signaling in U-87MG cells
AUTHORS: Zatkova, M., Z. Bacova, F. Puerta, Z. Lestanova, M. Alanazi, A. Kiss, A. Reichova, A.M. Castejon, D. Ostatnikova, and J. Bakos ABSTRACT: Neuropeptide oxytocin contributes to the regulation of glial cell morphology. The precise mechanisms, however, are not yet fully understood. In the present study, we have investigated whether an oxytocin-induced increase of intracellular
- 1. FEBRUARY 2018
Etiopathogenesis of autism – current state of knowledge (Etiopatogenéza autizmu – súčasný stav poznania)
AUTHORS: Važan, R., Belica, I., Ostatníková, D. ABSTRACT: Autism is a set of phenotypically heterogeneous neurodevelopmental conditions characterized by core symptoms in social communication, interactions, interests and repetitive stereotyped behaviour. Therefore, the term – autistic spectrum disorders, is preferred today. Due to the progress of autism in recent decades, a wide range of studies have
- 1. JUNE 2017
Vitamin D, neurosteroids and autism
AUTHORS: Macova, L., M. Bicikova, D. Ostatnikova, M. Hill, and L. Starka ABSTRACT: Vitamin D had been for a long time investigated for its effects onbone metabolism. Recently has been observed that the incidence of some neurodevelopmental disorders (including autism) increases hand in hand with vitamin D deficiency. Indeed, vitamin D was reported to modulate

- 1. JUNE 2017
Sex-dependent effects of letrozole on anxiety in middle-aged rats
AUTHORS: Borbelyova, V., E. Renczes Domonkos, M. Csongova, M. Kacmarova, D. Ostatnikova, P. Celec, and J. Hodosy ABSTRACT: Aromatase catalyzes the conversion of testosterone to estradiol and is involved in the physiological effects of sex hormones on brain function. Animal experiments have shown that the aromatase inhibitor, letrozole, can induce anxiety in young ovariectomized females
- 1. JUNE 2017
Fecal calprotectin levels correlate with main domains of the autism diagnostic interview-revised (ADI-R) in a sample of individuals with autism spectrum disorders from Slovakia
AUTHORS: Babinska, K., Tomova, A., Celusakova, H., Babkova, J., Repiska, G., Kubranska, A., Filcikova, D., Siklenkova, L., and Ostatnikova, D. ABSTRACT: Autism spectrum disorders (ASD) are neurodevelopmental disorders characterized by impaired social interaction and communication, as well as repetitive behavior and restricted interests. There is convincing evidence that the intestinal inflammation is involved in etiology
- 1. MAY 2017
Screening for autism spectrum disorders inpopulation of young children in Slovakia
AUTHORS: Hnilicová, S., Celušáková, H., Hnilica, P., Babinská, K., Pivovarčiová, A., Ostatníková, D. ABSTRACT: OBJECTIVES: The aim of our study was to assess efficacy of using M-CHAT R/F questionnaire for screening for Autism Spectrum Disorders (ASD) in a sample of Slovak population and compare it with objective diagnostic ASD tool ADI-R. M-CHAT R/T comparison with
- 1. MARCH 2017
What is the evidence of mitochondrial dysfunction in autism spectrum disorders?
AUTHORS: Babinská, K., Repiská, G., Gvozdjáková, A., Kucharská, J., Vokálová, L., Vidošovičová, M., Ostatníková,D. ABSTRACT: Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by impairments in social interaction and communication, combined with restricted and stereotyped patterns of behaviour and interests. There is an array of comorbid conditions associated with ASD. It has been suggested