• 1. JUNE 2017
    Vitamin D, neurosteroids and autism

    Vitamin D, neurosteroids and autism

    AUTHORS: Macova, L., M. Bicikova, D. Ostatnikova, M. Hill, and L. Starka ABSTRACT: Vitamin D had been for a long time investigated for its effects onbone metabolism. Recently has been observed that the incidence of some neurodevelopmental disorders (including autism) increases hand in hand with vitamin D deficiency. Indeed, vitamin D was reported to modulate
    • 1. JUNE 2017
    Sex-dependent effects of letrozole on anxiety in middle-aged rats

    Sex-dependent effects of letrozole on anxiety in middle-aged rats

    AUTHORS: Borbelyova, V., E. Renczes Domonkos, M. Csongova, M. Kacmarova, D. Ostatnikova, P. Celec, and J. Hodosy ABSTRACT: Aromatase catalyzes the conversion of testosterone to estradiol and is involved in the physiological effects of sex hormones on brain function. Animal experiments have shown that the aromatase inhibitor, letrozole, can induce anxiety in young ovariectomized females