• 2. NOVEMBER 2020
    A novel UHPLC-MS method targeting urinary metabolomic markers for autism spectrum disorder

    A novel UHPLC-MS method targeting urinary metabolomic markers for autism spectrum disorder

    AUTHORS: Olešová, D., Galba, J., Piešťanský, J., Celušáková, H., Repiská, G., Babinská, K., Ostatníková, D., Katina, S. and Kováč, A. ABSTRACT: Autism spectrum disorder is a heterogeneous neurodevelopmental disease. Currently, no biomarker of this disease is known. Diagnosis is performed through observation, standardized behavioral scales, and interviews with parents. In practice, diagnosis is often delayed

    • 25. OCTOBER 2020
    Detection of disease-associated microRNAs – application for autism spectrum disorders

    Detection of disease-associated microRNAs – application for autism spectrum disorders

    AUTHORS: Konečná, B., Radošinská, J., Keményová, P. and Repiská, G. ABSTRACT: Autism spectrum disorders (ASD) diagnostic procedure still lacks a uniform biological marker. This review gathers the information on microRNAs (miRNAs) specifically as a possible source of biomarkers of ASD. Extracellular vesicles, and their subset of exosomes, are believed to be a tool of cell-to-cell