2020 | Akademické centrum výskumu autizmu

- 1. DECEMBER 2020
Abnormal neuronal morphology and altered synaptic proteins are restored by oxytocin in autism-related SHANK3 deficient model
AUTHORS: Reichová, A., Bačová, Z., Bukatová, S., Kokavcová, M., Melišková, V., Frimmel, K., Ostatníková, D. and Bakoš, J. ABSTRACT: Oxytocin has been suggested as a potential therapeutic agent in autism and other neuropsychiatric conditions. Although, the link between the deficit in “SH3 domain and ankyrin repeat containing protein 3” (SHANK3) and autism spectrum disorders is
- Barbara Rašková
- 2020,
- Publications
- 2. NOVEMBER 2020
A novel UHPLC-MS method targeting urinary metabolomic markers for autism spectrum disorder
AUTHORS: Olešová, D., Galba, J., Piešťanský, J., Celušáková, H., Repiská, G., Babinská, K., Ostatníková, D., Katina, S. and Kováč, A. ABSTRACT: Autism spectrum disorder is a heterogeneous neurodevelopmental disease. Currently, no biomarker of this disease is known. Diagnosis is performed through observation, standardized behavioral scales, and interviews with parents. In practice, diagnosis is often delayed
- Barbara Rašková
- 2020,
- Publications

- 25. OCTOBER 2020
Detection of disease-associated microRNAs – application for autism spectrum disorders
AUTHORS: Konečná, B., Radošinská, J., Keményová, P. and Repiská, G. ABSTRACT: Autism spectrum disorders (ASD) diagnostic procedure still lacks a uniform biological marker. This review gathers the information on microRNAs (miRNAs) specifically as a possible source of biomarkers of ASD. Extracellular vesicles, and their subset of exosomes, are believed to be a tool of cell-to-cell
- Barbara Rašková
- 2020,
- Publications
- 6. OCTOBER 2020
Testosterone and the brain: from cognition to Autism
AUTHORS: Ostatníková, D., Lakatošová, S., Babková, J., Hodosy, J. and Celec, P. ABSTRACT: Sex and gender matter in all aspects of life. Humans exhibit sexual dimorphism in anatomy, physiology, but also pathology. Many of the differences are due to sex chromosomes and, thus, genetics, other due to endocrine factors such as sex hormones, some are
- Barbara Rašková
- 2020,
- Publications

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