2020 – Akademické centrum výskumu autizmu

- 1. DECEMBER 2020
Abnormal neuronal morphology and altered synaptic proteins are restored by oxytocin in autism-related SHANK3 deficient model
AUTHORS: Reichová, A., Bačová, Z., Bukatová, S., Kokavcová, M., Melišková, V., Frimmel, K., Ostatníková, D. and Bakoš, J. ABSTRACT: Oxytocin has been suggested as a potential therapeutic agent in autism and other neuropsychiatric conditions. Although, the link between the deficit in “SH3 domain and ankyrin repeat containing protein 3” (SHANK3) and autism spectrum disorders is
- Barbara Rašková
- 2020,
- Publications
- 2. NOVEMBER 2020
A novel UHPLC-MS method targeting urinary metabolomic markers for autism spectrum disorder
AUTHORS: Olešová, D., Galba, J., Piešťanský, J., Celušáková, H., Repiská, G., Babinská, K., Ostatníková, D., Katina, S. and Kováč, A. ABSTRACT: Autism spectrum disorder is a heterogeneous neurodevelopmental disease. Currently, no biomarker of this disease is known. Diagnosis is performed through observation, standardized behavioral scales, and interviews with parents. In practice, diagnosis is often delayed
- Barbara Rašková
- 2020,
- Publications
- 25. OCTOBER 2020
Detection of disease-associated microRNAs – application for autism spectrum disorders
AUTHORS: Konečná, B., Radošinská, J., Keményová, P. and Repiská, G. ABSTRACT: Autism spectrum disorders (ASD) diagnostic procedure still lacks a uniform biological marker. This review gathers the information on microRNAs (miRNAs) specifically as a possible source of biomarkers of ASD. Extracellular vesicles, and their subset of exosomes, are believed to be a tool of cell-to-cell
- Barbara Rašková
- 2020,
- Publications
- 6. OCTOBER 2020
Testosterone and the brain: from cognition to Autism
AUTHORS: Ostatníková, D., Lakatošová, S., Babková, J., Hodosy, J. and Celec, P. ABSTRACT: Sex and gender matter in all aspects of life. Humans exhibit sexual dimorphism in anatomy, physiology, but also pathology. Many of the differences are due to sex chromosomes and, thus, genetics, other due to endocrine factors such as sex hormones, some are
- Barbara Rašková
- 2020,
- Publications

- 23. SEPTEMBER 2020
Autism specrum disorders symptoms in pre-school girls (Špecifiká prejavov porúch autistického spektra u dievčat predškolského veku)
AUTHORS: Čelárová, D., Celušáková, H., Szapuová, Ž. and Ostatníková, D. ABSTRACT: Autism spectrum disorders are more common in males than females. Cause of this ratio is unknown and has been ascribed to hormonal (extreme male brain theory) or genetic (female protective model) etiology. One of the plausible explanations is the ability of girls to better
- Barbara Rašková
- 2020,
- Publications
- 1. SEPTEMBER 2020
Do „autistic traits“ determine our career choice?
AUTORI: Kyselicová, K., Čelárová, D., Celušáková, H., Janšáková, K., Greguš, M., Neščáková, E., Ostatníková, D. ABSTRACT: Objectives: Autistic traits may display a continuous distribution throughout the population. The aim of the present study was to assess the prevalence of autistic traits in university students and look for possible cognitive or behavioral differences between students of
- 1. AUGUST 2020
Specificity of gut microbiota in children with autism spectrum disorder in Slovakia and its correlation with astrocytes activity marker and specific behavioural patterns
AUTHORS: Sashova Tomova, A., Soltys, K., Repiska, G., Palkova, L., Celarova, D., Minarik, G., Turna, J., Prochotska, K., Babinska, K., Ostatnikova, D ABSTRACT: Recent research suggests the involvement of bidirectional gut-brain axis in autism spectrum disorder (ASD). The aim of this study was to establish the role of changed gut microbiota in behavioural and gastrointestinal
- 1. JUNE 2020
Gastrointestinal symptoms and feeding problems and their associations with dietary interventions, food supplement use and behavioral characteristics in a sample of children and adolescents with autism spectrum disorders
AUTHORS: Babinska, K., Celusakova, H., Belica, I., Szapuova, Z., Waczulikova, I., Nemcsicsova, D., Tomova, A., Ostatnikova, D. ABSTRACT: Autism spectrum disorders (ASD) are characterized by impairments in social interaction, communication, and restricted, stereotyped behavior. Gastrointestinal (GI), nutritional, and feeding problems are often reported in ASD. We investigated the prevalence of GI symptoms, food selectivity, and