AUTHORS: Hnilicov\u00e1, S., Celu\u0161\u00e1kov\u00e1, H., Hnilica, P., Babinsk\u00e1, K., Pivovar\u010diov\u00e1, A., Ostatn\u00edkov\u00e1, D.<\/p>\n
ABSTRACT: OBJECTIVES<\/span>: The aim of our study was to assess efficacy of using M-CHAT R\/F question<\/span>naire for screening for Autism Spectrum Disorders (ASD) in a sample of Slovak population <\/span>and compare it with objective diagnostic ASD tool ADI-R. M-CHAT R\/T comparison with <\/span>ADOS-2 diagnostic tool will be published and discussed elsewhere.<\/span> Activitas Nervosa Superior Rediviva. – Vol. 59, No. 1 (2017), s. 29-32. – ISSN (print) 1337-933X<\/p>\n
METHODS<\/span>: 92 children with ASD, 72 boys (91.2%), and 20 girls (8.9%), age 1.0\u20136.9 years, <\/span>who were signed up by their parents for ASD testing at our institution from 2013 to 2016 <\/span>were enrolled. All participants were screened by M-CHAT questionnaire filled out by a <\/span>parent and then complex psychological assessment by trained staff was performed. Latter <\/span>evaluation included ASD diagnostic tools: Autism Diagnostic Observation Schedule \u2013 sec<\/span>ond revision (ADOS-2) and Autism Diagnostic Interview-Revised (ADI-R).<\/span>
RESULTS<\/span>: Significant difference of total (sum) score of M-CHAT means between group <\/span>of children with ASD and without ASD (as diagnosed by using ADOS and ADI-R) was <\/span>observed (<\/span>p<<\/span>0.001). M-CHAT total score significantly correlated with ADI-R A Domain <\/span>Abnormalities in Reciprocal Social Interaction, (r=0.583;<\/span> p<<\/span>0.01); ADI-R B Domain \u2013 <\/span>Qualitative Abnormalities in Communication (r=0.357;<\/span> p<<\/span>0.01).<\/span>
CONCLUSION<\/span>: We demonstrated that in our sample of Slovak children M-CHAT total score <\/span>can be used to differentiate between children with and without ASD risk. M-CHAT also <\/span>well correlated with accepted objective measure for diagnosis of ASD, i.e. ADI-R. Future <\/span>work is needed to determine the sensitivity and specificity of M-CHAT in screening for <\/span>ASD in general population of children in Slovakia.<\/span><\/p>\n