Sledovanie por\u00fach sp\u00e1nku a\u00a0koncentr\u00e1cie 6-sulfatoxymelaton\u00ednu v\u00a0mo\u010di det\u00ed s\u00a0poruchami autistick\u00e9ho spektra [vc_row][vc_column][vc_column_text]Deti s\u00a0PAS m\u00e1vaj\u00fa \u010dasto probl\u00e9my so sp\u00e1nkom. Ich pr\u00ed\u010diny m\u00f4\u017eu by\u0165 r\u00f4zne, jedna\u00a0z\u00a0te\u00f3ri\u00ed predpoklad\u00e1 naru\u0161enie cirkadi\u00e1nnych rytmov (tzv. vn\u00fatorn\u00fdch biologick\u00fdch hod\u00edn). Pre t\u00fato te\u00f3riu sved\u010dia zisten\u00e9 odli\u0161nosti v\u00a0hladin\u00e1ch melaton\u00ednu – horm\u00f3nu, ktor\u00fd sa podie\u013ea na regul\u00e1cii biorytmov v\u00a0z\u00e1vislosti od zmien intenzity svetla po\u010das d\u0148a a\u00a0noci…. Viac Na projekte spolupracujeme s\u00a0Katedrou \u017eivo\u010d\u00ed\u0161nej fyziol\u00f3gie a etol\u00f3gie\u00a0Pr\u00edrodovedeckej fakulty<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_eb_attr":"","footnotes":""},"class_list":["post-21222","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/acva.sk\/en\/wp-json\/wp\/v2\/pages\/21222","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/acva.sk\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/acva.sk\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/acva.sk\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/acva.sk\/en\/wp-json\/wp\/v2\/comments?post=21222"}],"version-history":[{"count":0,"href":"https:\/\/acva.sk\/en\/wp-json\/wp\/v2\/pages\/21222\/revisions"}],"wp:attachment":[{"href":"https:\/\/acva.sk\/en\/wp-json\/wp\/v2\/media?parent=21222"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\nCie\u013eom \u0161t\u00fadie bolo porovna\u0165 v\u00fdskyt por\u00fach sp\u00e1nku u\u00a0det\u00ed s\u00a0autizmom a\u00a0de\u0165mi z\u00a0be\u017enej popul\u00e1cie. U\u00a0det\u00ed s\u00a0PAS sme sa zamerali aj na rozdiely v biorytme zmien hlad\u00edn 6-sulfatoxymelaton\u00ednu (aMT6s), ktor\u00fd je metabolitom melaton\u00ednu, vo vzorke rann\u00e9ho a\u00a0poobedn\u00e9ho mo\u010du. Poruchy sp\u00e1nku sme zistili u\u00a065% det\u00ed bez PAS, u\u00a0det\u00ed s\u00a0PAS bol ich v\u00fdskyt a\u017e 80 %. Na\u0161e v\u00fdsledky nazna\u010duj\u00fa odli\u0161nosti v\u00a0biorytme vylu\u010dovania melaton\u00ednu u\u00a0det\u00ed s\u00a0PAS. Charakterizuje ich menej v\u00fdrazn\u00fd no\u010dn\u00fd vzostup v\u00a0porovnan\u00ed s\u00a0neurotypick\u00fdmi de\u0165mi.
\nBabinska K, Siklenkova L, Stebelova K, Waczulikova I, Celusakova H, Vidosovicova M, Bartakovicova K, Szapuova Z, Kemenyova P. Urinary levels of 6-sulphatoxymelatonin and their associations with sleep disorders and behavioural impairments in children with autism spectrum disorder. Bratisl Lek Listy. 2019;120(11):849-855.<\/em>[\/vc_column_text][\/vc_column][\/vc_row]\n","protected":false},"excerpt":{"rendered":"